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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1908 1
1909 1
1910 1
1911 1
1912 1
1914 1
1915 2
1916 8
1917 2
1918 4
1919 2
1921 3
1922 5
1923 6
1924 1
1925 2
1926 3
1927 2
1928 5
1929 9
1930 10
1931 4
1932 8
1933 3
1934 2
1935 4
1936 4
1937 5
1938 6
1939 9
1940 6
1941 8
1942 4
1943 5
1944 2
1945 10
1946 11
1947 11
1948 20
1949 9
1950 14
1951 12
1952 15
1953 21
1954 30
1955 41
1956 28
1957 36
1958 40
1959 54
1960 54
1961 83
1962 90
1963 104
1964 137
1965 162
1966 173
1967 220
1968 266
1969 294
1970 322
1971 372
1972 432
1973 520
1974 558
1975 1772
1976 1694
1977 1688
1978 1641
1979 1773
1980 1908
1981 2113
1982 2267
1983 2969
1984 3106
1985 3442
1986 3734
1987 3716
1988 3702
1989 4286
1990 4348
1991 4249
1992 4317
1993 4320
1994 4397
1995 4287
1996 4381
1997 4064
1998 3847
1999 3810
2000 3769
2001 3801
2002 3557
2003 3615
2004 3513
2005 3640
2006 3504
2007 3485
2008 3460
2009 3456
2010 3465
2011 3467
2012 3533
2013 3517
2014 3383
2015 3494
2016 3256
2017 3121
2018 3021
2019 2991
2020 3217
2021 3421
2022 3195
2023 2784
2024 1076

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160,645 results

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Page 1
Antibody Co-Administration Can Improve Systemic and Local Distribution of Antibody-Drug Conjugates to Increase In Vivo Efficacy.
Ponte JF, Lanieri L, Khera E, Laleau R, Ab O, Espelin C, Kohli N, Matin B, Setiady Y, Miller ML, Keating TA, Chari R, Pinkas J, Gregory R, Thurber GM. Ponte JF, et al. Mol Cancer Ther. 2021 Jan;20(1):203-212. doi: 10.1158/1535-7163.MCT-20-0451. Epub 2020 Nov 11. Mol Cancer Ther. 2021. PMID: 33177153 Free PMC article.
An antibody that cross-reacts with human and murine FRalpha was generated and tested in an animal model where the antibody/ADC bind both human tumor FRalpha and mouse FRalpha in normal tissue. ...By reducing target-antigen-mediated clearance in normal …
An antibody that cross-reacts with human and murine FRalpha was generated and tested in an animal model where the antibody/ADC …
Antibody therapy reverses biological signatures of COVID-19 progression.
Maher MC, Soriaga LB, Gupta A, Chen YP, di Iulio J, Ledoux S, Smithey MJ, Cathcart AL, McKusick K, Sun D, Aldinger M, Alexander E, Purcell L, Ding X, Peppercorn A, Austin D, Mogalian E, Yeh WW, Shapiro AE, Corti D, Virgin HW, Pang PS, Telenti A. Maher MC, et al. Cell Rep Med. 2022 Aug 16;3(8):100721. doi: 10.1016/j.xcrm.2022.100721. Cell Rep Med. 2022. PMID: 35977462 Free PMC article. Clinical Trial.
We study correlates of disease severity in the COMET-ICE clinical trial that randomized 1:1 to placebo or to sotrovimab, a monoclonal antibody for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (ClinicalTrials.gov04545060). ...We id …
We study correlates of disease severity in the COMET-ICE clinical trial that randomized 1:1 to placebo or to sotrovimab, a monoclonal ant …
Discovery of novel antibody-drug conjugates bearing tissue protease specific linker with both anti-angiogenic and strong cytotoxic effects.
Li Y, Si R, Wang J, Hai P, Zheng Y, Zhang Q, Pan X, Zhang J. Li Y, et al. Bioorg Chem. 2023 Aug;137:106575. doi: 10.1016/j.bioorg.2023.106575. Epub 2023 Apr 26. Bioorg Chem. 2023. PMID: 37148706
Bevacizumab is an FDA-approved class of monoclonal antibodies used to inhibit angiogenesis and promote normalization of blood vessels. ...However, the whole-body toxicities and toxicity associated with chemotherapy greatly limit the clinical use of this combination …
Bevacizumab is an FDA-approved class of monoclonal antibodies used to inhibit angiogenesis and promote normalization of blood …
Trastuzumab-induced hepatotoxicity.
Srinivasan S, Parsa V, Liu CY, Fontana JA. Srinivasan S, et al. Ann Pharmacother. 2008 Oct;42(10):1497-501. doi: 10.1345/aph.1L217. Epub 2008 Sep 9. Ann Pharmacother. 2008. PMID: 18780811
LFTs showed enzyme levels rising again and trastuzumab was discontinued after 2 cycles, with subsequent normalization of the levels. She was then treated with weekly paclitaxel and her LFT values continued to be in the near-normal range. DISCUSSION: There were no co …
LFTs showed enzyme levels rising again and trastuzumab was discontinued after 2 cycles, with subsequent normalization of the levels. …
In-Use Interfacial Stability of Monoclonal Antibody Formulations Diluted in Saline i.v. Bags.
Kannan A, Shieh IC, Hristov P, Fuller GG. Kannan A, et al. J Pharm Sci. 2021 Apr;110(4):1687-1692. doi: 10.1016/j.xphs.2020.10.036. Epub 2020 Oct 22. J Pharm Sci. 2021. PMID: 33141046
The use of monoclonal antibodies (mAbs) for the treatment of a variety of diseases is rapidly growing each year. Many mAbs are administered intravenously using i.v. bags containing 0.9% NaCl (normal saline). We studied the aggregation propensity of these antibody …
The use of monoclonal antibodies (mAbs) for the treatment of a variety of diseases is rapidly growing each year. Many mAbs are admini …
Past, present, and future of anti-IgE biologics.
Guntern P, Eggel A. Guntern P, et al. Allergy. 2020 Oct;75(10):2491-2502. doi: 10.1111/all.14308. Epub 2020 Apr 21. Allergy. 2020. PMID: 32249957 Free PMC article. Review.
The initial concept of specific IgE targeting through the use of anti-IgE antibodies has gained a lot of momentum and within a few years independent research groups have reported successful generation of first murine monoclonal anti-IgE antibodies. Subsequent genera …
The initial concept of specific IgE targeting through the use of anti-IgE antibodies has gained a lot of momentum and within a few ye …
Campath-1H (anti-CD52) monoclonal antibody therapy in lymphoproliferative disorders.
Pangalis GA, Dimopoulou MN, Angelopoulou MK, Tsekouras C, Vassilakopoulos TP, Vaiopoulos G, Siakantaris MP. Pangalis GA, et al. Med Oncol. 2001;18(2):99-107. doi: 10.1385/mo:18:2:99. Med Oncol. 2001. PMID: 11778765 Review.
Campath-1H is a humanized monoclonal antibody targeted against the CDw52 membrane antigen of lymphocytes, which causes complement and antibody-dependent cell-mediated cytotoxicity. ...The median duration of response is 9-12 mo. Because of the antibody's …
Campath-1H is a humanized monoclonal antibody targeted against the CDw52 membrane antigen of lymphocytes, which causes complement and …
RI-002, an intravenous immunoglobulin containing high titer neutralizing antibody to RSV and other respiratory viruses for use in primary immunodeficiency disease and other immune compromised populations.
Wasserman RL, Greener BN, Mond J. Wasserman RL, et al. Expert Rev Clin Immunol. 2017 Dec;13(12):1107-1119. doi: 10.1080/1744666X.2017.1389647. Epub 2017 Oct 16. Expert Rev Clin Immunol. 2017. PMID: 29035131 Free PMC article. Review.
Novel immune globulin (IG) products (RI-002, RI-001) have been designed to provide protection against respiratory syncytial virus (RSV) mediated respiratory illness while at the same time meeting the manufacturing requirements established by FDA for antibody supplementatio …
Novel immune globulin (IG) products (RI-002, RI-001) have been designed to provide protection against respiratory syncytial virus (RSV) medi …
Enduring antibody responses in "normal" rabbits to maternal immunoglobulin allotypes.
Adler FL, Noelle RJ. Adler FL, et al. J Immunol. 1975 Sep;115(3):620-5. J Immunol. 1975. PMID: 1151069
A majority of rabbits born to mothers heterozygous with respect to the b locus allotypic markers "spontaneously" develop antibodies against the noninherited maternal allotypes. Such antibodies generally appear in the 4- to 5-month-old rabbit, after what may be a tra …
A majority of rabbits born to mothers heterozygous with respect to the b locus allotypic markers "spontaneously" develop antibodies a …
160,645 results
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